| Amino Acid Sequence of Human p27 /Kip-1: 198 aa, MW 22073 Da , Cellular component: Note=Nuclear and cytoplasmic in quiescent cells. Upon cell cycle progression, mostly cytoplasmic. | ||
| Molecular function: Involved in G1 arrest. May mediate TGF beta-induced G1 arrest. Binds to and inhibits complexes formed by cyclin E-CDK2, cyclin A-CDK2, and cyclin D1-CDK4. Interaction with nucleoporin NUP50 is required for nuclear import and for degradation of phosphorylated p27Kip1 after nuclear import ; Swiss ID: P46527 | ||
10 20 30 40 50 60
MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW
70 80 90 100 110 120
NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQESQDVS GSRPAAPLIG
130 140 150 160 170 180
APANSEDTHL VDPKTDPSDS QTGLAEQCAG IRKRPATDDS STQNKRANRT EENVSDGSPN
190
AGSVEQTPKK PGLRRRQT 198 |
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Immunohistochemical analysis of paraffin
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Product Name |
Immunogen | Species | Host | Application | Catalog No. |
Quantity |
Price ($) |
|---|---|---|---|---|---|---|---|
| Total p27 ELISA Kit | h |
ELISA, cell culture only |
PS001-32-SK-H-01 |
96 |
450 |
||
| Total p27 ELISA Kit | h |
ELISA, cell culture only |
PS001-32-SK-H-01 |
192 |
800 |
||
| p27 RMAB Antibody | C-terminal p27 |
h, r |
rabbit |
IHC, IFC, WB |
PS001-32-AG-01 |
50 ul |
280 |
| Phosphorylated-Ser 10 , p27 RMAB Antibody | Phosphor specific peptide Ser10 |
h, r, m |
rabbit |
IHC, WB |
PS001-32-AG-02 |
50 ul |
280 |
| p27 Polyclonal Antibody | C-terminal p27 |
h, r, m |
rabbit |
IHC, IFC, WB |
PS001-32-AG-03 |
50 ug |
160 |